Garlic Supplementation Reduces Circulating C-reactive Protein, Tumour Necrosis Factor, and Interleukin-6 in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Mofrad, et al, 2019

The systematic review and meta-analysis included 16 random, controlled trials which evaluated garlic treatment on inflammatory biomarkers in adults. The treatments ranged from 12 to 3600mg garlic daily over 2 to 52 weeks. A significant reduction in C-reactive protein, interleukin-6 and Tumour Necrosis Factor compared to placebo was reported. However, adiponectin and leptin status were unchanged.

Is selenium intake associated with the presence of depressive symptoms among US adults? Findings from National Health and Nutrition Examination Survey (NHANES) 2011–2014
Ghimire, et al, 2019

The cross-sectional investigation of the National Health and Nutrition Examination Survey analysed selenium intake using the 24-hour recall method and serum levels in relation to depressive episodes and anti-depressant use. A non-significant inverse association between serum selenium and depressive incidents.

Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality: An Individual-Level Pooled Analysis of 30 Cohort Studies.
Marklund, et al, 2019

An individual-pooled analysis of 30 cohort studies evaluated how in-vivo circulating and tissue levels of linoleic acid and arachidonic acid relate to incident cardiovascular disease across multiple international studies. The follow up duration of the selected studies ranged from 2.5 to 31.9 years, while 15,198 incident cardiovascular events occurred among 68,659 participants. It was reported that higher levels of linoleic acid were significantly associated with lowered risk of total cardiovascular disease, cardiovascular mortality and ischemic stroke.

The Role of Probiotics and Prebiotics in the Prevention and Treatment of Obesity
Cerdo, et al, 2019

Previous studies have shown the impact the microbiome has on adiposity; subsequently reports document the transfer of the microbiome from obese animals to lean animals triggers an increase in fat mass through metabolic changes. This review discusses the potential mechanisms underlying such changes and whether the physiological change can occur from lean to obese, which may contribute to clinical therapies.

Saffron (Crocus sativus L.) in Ocular Diseases: A Narrative Review of the Existing Evidence from Clinical Studies
Heitmar et al, 2019

Saffron, Latin: Crocus sativus L. and its phytonutrients are rich carotenoids reported to exert anti-inflammatory, pleiotropic, anti-oxidative and neuroprotective effects. An increasing number of research studies have investigated the effects and mechanistic pathways of these compounds in relation to ocular health. This review presents the key findings in this area of research.